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Lactic acid based products like Antica are exempted from the tolerance requirement of Japan and US. It is also classified by the Bureau of Food and Drugs(BFAD) as well as the Food and Drugs Administration (FDA) in the US as generally recognized as safe (GRAS) for use in food. The United States Environment Protection Agency also has determined that there would be no human health concerns and environmental concerns with the use of lactic acid food, cosmetic and agricultural applications.
Summary of Japanâ€™s New Positive List System for Regulation of Agricultural Chemical Residues 2006 included lactic acid based products to be exempted from the positive list regulation, because they do not show any adverse effects to human health.